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Skin Cancer Screening and Dermoscopy

Content owner/Author: Specialist Dr. Utkan Kızıltaç — Dermatology Specialist

Last medical review and update: September 10, 2026

Skin cancer evaluation is not simply about looking at a single mole. It requires a comprehensive assessment of individual and family risk, the number and pattern of moles, sun damage, and suspicious lesions. In high-risk patients, the frequency of follow-up is individualized.

Dermoscopy is a non-invasive method that helps to visualize pigment and vascular structures that are not visible to the naked eye by evaluating skin lesions under magnified and special lighting. When used by a trained clinician in melanoma evaluation, it significantly increases diagnostic accuracy compared to naked-eye examination.

Dermoscopy is not only used for moles; it can be helpful in melanoma, basal cell carcinoma, squamous cell carcinoma, actinic keratosis, and numerous benign or inflammatory lesions.

Dermoscopy is not a substitute for histopathology. Biopsy or appropriate excision may be necessary for suspicious lesions. In cases of suspected melanoma, diagnostic biopsy is planned to be deep enough to allow reliable assessment of Breslow thickness and to sample as much of the lesion as possible.

In high-risk patients with numerous or atypical nevi, total body photography and sequential digital dermoscopic imaging can help track changes in selected lesions over time. The goal is not to remove all moles, but to more accurately identify those that are changing or suspicious.

The evidence is insufficient to justify routine screening at the same intervals for everyone in the general asymptomatic population; however, this does not negate the value of regular dermatological monitoring in high-risk individuals.

Dermatologist's Note

One of the most important contributions of dermoscopy is its ability to more accurately identify truly suspicious lesions while reducing unnecessary excisions. The decision is not made solely based on the question of "am I large?".

Frequently Asked Questions

Does dermoscopy hurt? No; it's non-invasive.

Does dermoscopy definitively show cancer? Histopathology may be necessary for suspicious lesions.

Should every mole be removed? No.

Is the phone app sufficient? No; it does not replace a clinical examination and dermoscopy.

Scientific Resources

Dinnes J, Deeks JJ, Chuchu N, et al. Dermoscopy, with and without visual inspection, for diagnosing melanoma in adults. Cochrane Database Syst Rev. 2018;12:CD011902. PMID: 30521682. PMCID: PMC6517096. DOI: 10.1002/14651858.CD011902.pub2. https://pubmed.ncbi.nlm.nih.gov/30521682/

Lauters R, Brown AD, Harrington KCA. Melanoma: Diagnosis and Treatment. Am Fam Physician. 2024;110(4):367-377. PMID: 39418569. https://pubmed.ncbi.nlm.nih.gov/39418569/

US Preventive Services Task Force. Screening for Skin Cancer: Recommendation Statement. 2023. https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/skin-cancer-screening

American Academy of Dermatology. Melanoma clinical guideline. https://www.aad.org/member/clinical-quality/guidelines/melanoma

Dermatology Examination and Appointment

You can get information about dermatological evaluations and appointments for skin cancer screening and dermoscopy.